Cancer: durable remission without collateral damage
Finding and testing compounds and combinations that kill tumour cells while leaving healthy tissue intact.
In everyday words
Cancer is your own body's cells growing out of control and crowding out healthy tissue. We are looking for treatments that kill those runaway cells without harming the rest of you — whether that chemistry comes from a lab, a plant, or the sea. This work happens in labs and reviews, never as medical advice for a patient.
Open questions
- Which metabolic vulnerabilities are shared across resistant solid tumours?
- Can existing approved drugs be combined to starve tumours without new toxicity?
- Which plant-derived cytotoxins have a usable therapeutic window in humans?
Current leads
Repurposed antiparasitics in glioma models
Repurposed drugOpen replication requested — three labs have posted conflicting results.
Plainly: Drugs already approved to kill parasites might also slow brain tumours. Three labs disagree with each other, so the tests need to be repeated properly before anyone can trust the answer.
Marine-sponge alkaloid scaffolds
Natural sourceStructure-activity data being collected from published isolates.
Plainly: Sea sponges make chemicals that are extremely good at killing specific cells. We are collecting which ones do what, to see if any can be turned into a usable drug.
Metabolic co-inhibition pairs
Man-madeCandidate pairs ranked, awaiting accredited in vitro assessment.
Plainly: Tumours burn a lot of fuel. Blocking two fuel sources at once may starve them — but it needs lab tests first to prove it is safe for healthy tissue.
Safety note
No lead leaves this page as a treatment suggestion. Every lead is a research hypothesis pending accredited laboratory assessment.